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Article

Modulation of Tumor-Associated Macrophages (TAM) Phenotype by Platelet-Activating Factor (PAF) Receptor.

Journal of immunology research - 1 Jan 2017

da Silva Junior Ildefonso Alves, Stone Simone Cardozo, Rossetti Renata Marques, Jancar Sonia, Lepique Ana Paula

Abstract excerpt

Platelet-activating factor (PAF) plays an important role in the pathogenesis of several types of tumors. The biological effects of PAF are mediated by the PAF receptor (PAFR), which can be expressed by tumor cells and host cells that infiltrate the tumor microenvironment. In the present study, we investigated the role of PAFR expressed by leukocytes that infiltrate two types of tumors, one that expresses PAFR...

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Identifiers

PMID: 29445756
DOI: 10.1155/2017/5482768
PMCID: PMC5763242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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