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Article

Alternative activation of tumor-associated macrophages by IL-4: priming for protumoral functions.

Cell cycle (Georgetown, Tex.) - 15 Dec 2010

Wang Hao-Wei, Joyce Johanna A

Abstract excerpt

Although macrophages were originally recognized as major immune effector cells, it is now appreciated that they also play many important roles in the maintenance of tissue homeostasis, and are involved in a variety of pathological conditions including cancer. Several studies have demonstrated the contributions of tumor-associated macrophages (TAMs) to tumor initiation, progression, and metastasis. However, the...

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Identifiers

PMID: 21150330
DOI: 10.4161/cc.9.24.14322
PMCID: PMC3047808

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Source receipt: pubmed, retrieved 7 Sept 2026.

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