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Article

PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homoeostasis.

Clinical science (London, England : 1979) - 1 Apr 2016

Filgueiras Luciano Ribeiro, Koga Marianna Mainardi, Quaresma Paula G, Ishizuka Edson Kiyotaka, Montes Marlise B A, Prada Patricia O, Saad Mario J, Jancar Sonia, Rios Francisco J

Abstract excerpt

Metabolic dysfunction is associated with adipose tissue inflammation and macrophage infiltration. PAFR (platelet-activating factor receptor) is expressed in several cell types and binds to PAF (platelet-activating factor) and oxidized phospholipids. Engagement of PAFR in macrophages drives them towards the anti-inflammatory phenotype. In the present study, we investigated whether genetic deficiency of PAFR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26785675
DOI: 10.1042/CS20150538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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