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Article

Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy.

BMC cancer - 13 May 2010

de Oliveira Soraya I, Andrade Luciana N S, Onuchic Ana C, Nonogaki Sueli, Fernandes Patrícia D, Pinheiro Mônica C, Rohde Ciro B S, Chammas Roger, Jancar Sonia

Abstract excerpt

BACKGROUND: Phagocytosis of apoptotic cells by macrophages induces a suppressor phenotype. Previous data from our group suggested that this occurs via Platelet-activating factor receptor (PAF-R)-mediated pathways. In the present study, we investigated the impact of apoptotic cell inoculation or induction by a chemotherapeutic agent (dacarbazine, DTIC) on tumour growth, microenvironmental parameters and survival,...

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Identifiers

PMID: 20465821
DOI: 10.1186/1471-2407-10-200
PMCID: PMC2881890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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