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Article

Models of epigenetic age capture patterns of DNA methylation in glioma associated with molecular subtype, survival, and recurrence

16 Jan 2018

Abstract excerpt

Background: Models of epigenetic aging (epigenetic clocks) have been implicated as potentially useful markers for cancer risk and prognosis. Using 2 previously published methods for modeling epigenetic age, Horvath's clock and epiTOC, we investigated epigenetic aging patterns related to World Health Organization grade and molecular subtype as well as associations of epigenetic aging with glioma survival and...

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Share to Epigenetics and DNA Methylation
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PMID: 29432558
DOI: 10.1093/neuonc/noy003

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