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Article

Interactions of Age and Blood Immune Factors and Noninvasive Prediction of Glioma Survival.

Journal of the National Cancer Institute - 8 Mar 2022

Molinaro Annette M, Wiencke John K, Warrier Gayathri, Koestler Devin C, Chunduru Pranathi, Lee Ji Yoon, Hansen Helen M, Lee Sean, Anguiano Joaquin, Rice Terri, Bracci Paige M, McCoy Lucie, Salas Lucas A, Christensen Brock C, Wrensch Margaret, Kelsey Karl T, Taylor Jennie W, Clarke Jennifer L

Abstract excerpt

BACKGROUND: Tumor-based classification of human glioma portends patient prognosis, but considerable unexplained survival variability remains. Host factors (eg, age) also strongly influence survival times, partly reflecting a compromised immune system. How blood epigenetic measures of immune characteristics and age augment molecular classifications in glioma survival has not been investigated. We assess the...

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Identifiers

PMID: 34597382
DOI: 10.1093/jnci/djab195
PMCID: PMC8902347

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