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Article

SLE-Associated Defects Promote Altered T Cell Function.

Critical reviews in immunology - 1 Jan 2017

Crispin Jose C, Hedrich Christian M, Suárez-Fueyo Abel, Comte Denis, Tsokos George C

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease linked to profound defects in the function and phenotype of T lymphocytes. Here, we describe abnormal signaling pathways that have been documented in T cells from patients with SLE and discuss how they impact gene expression and immune function, in order to understand how they contribute to disease development and progression.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

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Identifiers

PMID: 29431078
DOI: 10.1615/CritRevImmunol.2018025213
PMCID: PMC6314197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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