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Article

Pathways leading to an immunological disease: systemic lupus erythematosus.

Rheumatology (Oxford, England) - 1 Apr 2017

Zharkova Olga, Celhar Teja, Cravens Petra D, Satterthwaite Anne B, Fairhurst Anna-Marie, Davis Laurie S

Abstract excerpt

SLE is a chronic autoimmune disease caused by perturbations of the immune system. The clinical presentation is heterogeneous, largely because of the multiple genetic and environmental factors that contribute to disease initiation and progression. Over the last 60 years, there have been a number of significant leaps in our understanding of the immunological mechanisms driving disease processes. We now know that...

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Identifiers

PMID: 28375453
DOI: 10.1093/rheumatology/kew427
PMCID: PMC5410978

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Source receipt: pubmed, retrieved 7 Sept 2026.

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