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Article

Transcriptome analysis and prognosis of ALDH isoforms in human cancer.

Scientific reports - 9 Feb 2018

Chang Peter Mu-Hsin, Chen Che-Hong, Yeh Chi-Chun, Lu Hsueh-Ju, Liu Tze-Tze, Chen Ming-Huang, Liu Chun-Yu, Wu Alexander T H, Yang Muh-Hwa, Tai Shyh-Kuan, Mochly-Rosen Daria, Huang Chi-Ying F

Abstract excerpt

Overexpression of ALDH is associated with cancer stem-like features and poor cancer prognosis. High ALDH activity has been observed in cancer stem-like cells. There are a total of 19 human ALDH isoforms, all of which are associated with reducing oxidative stress and protecting cells from damage. However, it is unknown whether all ALDHs are associated with poor cancer prognosis and which ones play a significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29426835
DOI: 10.1038/s41598-018-21123-4
PMCID: PMC5807355

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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