Article
ALDH2 gene polymorphism in different types of cancers and its clinical significance.
Life sciences - 15 Feb 2016
Li Rui, Zhao Zihan, Sun Mingyang, Luo Jiachi, Xiao Yechen
Abstract excerpt
Aldehyde dehydrogenase 2 (ALDH2), an important mitochondrial enzyme governing ethanol metabolism, displays polymorphism in human. Recent evidence suggested that genetic polymorphism in ALDH2 gene may be significantly correlated with the susceptibility to cancer, such as colorectal cancer, esophageal cancer, and liver cancer. To investigate the correlation between ALDH2 mutant gene and the risk of a certain...
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