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ALDEFLUOR activity, ALDH isoforms, and their clinical significance in cancers

18 Jan 2023

Abstract excerpt

High aldehyde dehydrogenase (ALDH) activity is a metabolic feature of adult stem cells and various cancer stem cells (CSCs). The ALDEFLUOR system is currently the most commonly used method for evaluating ALDH enzyme activity in viable cells. This system is applied extensively in the isolation of normal stem cells and CSCs from heterogeneous cell populations. For many years, ALDH1A1 has been considered the most...

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PMID: 36651035
DOI: 10.1080/14756366.2023.2166035

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