Article
Prioritizing disease genes with an improved dual label propagation framework.
BMC bioinformatics - 8 Feb 2018
Zhang Yaogong, Liu Jiahui, Liu Xiaohu, Fan Xin, Hong Yuxiang, Wang Yuan, Huang YaLou, Xie MaoQiang
Abstract excerpt
BACKGROUND: Prioritizing disease genes is trying to identify potential disease causing genes for a given phenotype, which can be applied to reveal the inherited basis of human diseases and facilitate drug development. Our motivation is inspired by label propagation algorithm and the false positive protein-protein interactions that exist in the dataset. To the best of our knowledge, the false positive...
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