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Exfoliation Syndrome: A Disease of Autophagy and LOXL1 Proteopathy

16 Mar 2018

Abstract excerpt

Exfoliation syndrome (XFS) is an age-related disease involving the deposition of aggregated fibrillar material (exfoliation material) at extracellular matrices in tissues that synthesize elastic fibers. Its main morbidity is in the eye, where exfoliation material accumulations form on the surface of the ciliary body, iris, and lens. Exfoliation glaucoma (XFG) occurs in a high proportion of persons with XFS and...

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PMID: 29547474
DOI: 10.1097/ijg.0000000000000919

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