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Article

LOXL1 folding in exfoliation glaucoma.

Advances in protein chemistry and structural biology - 1 Jan 2019

Bernstein Audrey M, Ritch Robert, Wolosin J Mario

Abstract excerpt

Exfoliation syndrome (XFS) is an age-related disease defined by the deposition of aggregated fibrous material (XFM) in the peri-cellular space. Principal morbidity occurs in the eye, where XFM accumulates on the anterior ocular tissues. GWAS have found that certain genetic variants of lysyl oxidase-like 1 (LOXL1), a matrix cross-linking enzyme that is required for elastic fiber formation confer risk for the...

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Identifiers

PMID: 31928728
DOI: 10.1016/bs.apcsb.2019.09.005
PMCID: PMC7589528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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