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Article

Pseudoexfoliation syndrome and glaucoma: from genes to disease mechanisms.

Current opinion in ophthalmology - 1 Mar 2021

Schlötzer-Schrehardt Ursula, Khor Chiea Chuen

Abstract excerpt

PURPOSE OF REVIEW: The genetic basis of pseudoexfoliation (PEX) syndrome, the most common identifiable cause of open-angle glaucoma, is steadily being elucidated. This review summarizes the recent advances on genetic risk factors for PEX syndrome/glaucoma and their potential functional implications in PEX pathophysiology. RECENT FINDINGS: As of today, seven loci associated with the risk of PEX surpassing...

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Identifiers

PMID: 33332884
DOI: 10.1097/ICU.0000000000000736

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