Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling

7 Feb 2018

Abstract excerpt

BMP2 expression is spatiotemporally correlated with embryo implantation and is crucial for endometrial decidualization and fertility in mice. BMP2 has been reported to increase the mesenchymal adhesion molecule N-cadherin and enhance cell invasion in cancer cells; moreover, studies suggest that N-cadherin promotes placental trophoblast invasion. However, whether BMP2 can promote trophoblast cell invasion during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Pregnancy and preeclampsia studies
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29416020
DOI: 10.1038/s41419-017-0230-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signalingPMID 29416020Read ↗

Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A ProductionSemantic proximity Read ↗

Bone morphogenetic protein 2 promotes human trophoblast cell invasion and endothelial‐like tube formation through ID1‐mediated upregulation of IGF binding protein‐3Semantic proximity Read ↗

GDF-11 promotes human trophoblast cell invasion by increasing ID2-mediated MMP2 expressionSemantic proximity Read ↗

Activin A, B, and AB Increase Human Trophoblast Cell Invasion by Up-regulating N-CadherinSemantic proximity Read ↗

Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expressionSemantic proximity Read ↗

Differential Role of Smad2 and Smad3 in the Acquisition of an Endovascular Trophoblast-Like Phenotype and Preeclampsia.Semantic proximity Read ↗

Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion MoleculesSemantic proximity Read ↗

Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women With Repeated Implantation FailureSemantic proximity Read ↗

CDX2 Enhances HTR-8/SVneo Trophoblast Cell Invasion by Altering the Expression of Matrix MetalloproteinasesSemantic proximity Read ↗

Transforming growth factor β1 promotes invasion of human JEG-3 trophoblast cells via TGF-β/Smad3 signaling pathwaySemantic proximity Read ↗

MSX2 Induces Trophoblast Invasion in Human PlacentaSemantic proximity Read ↗

TGFb-induced SMAD1/5 activation drives transient epithelial-to-mesenchymal transition in trophoblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.