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Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A Production

25 May 2018

Abstract excerpt

Bone morphogenetic protein (BMP) 2 and activin A belong to the TGF-β superfamily and are highly expressed in human endometrium and placenta. Studies have demonstrated that activin A and BMP2 play essential roles in the process of early embryo implantation by promoting human trophoblast cell invasion. However, whether activin A production can be regulated by BMP2 in human trophoblast cells remains unknown. The aim...

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PMID: 29846546
DOI: 10.1210/en.2018-00301

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Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A ProductionPMID 29846546Read ↗

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