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Article

MSX2 Induces Trophoblast Invasion in Human Placenta

18 Apr 2016

Abstract excerpt

Normal implantation depends on appropriate trophoblast growth and invasion. Inadequate trophoblast invasion results in pregnancy-related disorders, such as early miscarriage and pre-eclampsia, which are dangerous to both the mother and fetus. Msh Homeobox 2 (MSX2), a member of the MSX family of homeobox proteins, plays a significant role in the proliferation and differentiation of various cells and tissues,...

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PMID: 27088357
DOI: 10.1371/journal.pone.0153656

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Related research

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Research trail→

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MSX2 Induces Trophoblast Invasion in Human PlacentaPMID 27088357Read ↗

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GDF-11 promotes human trophoblast cell invasion by increasing ID2-mediated MMP2 expressionSemantic proximity Read ↗

STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in PreeclampsiaSemantic proximity Read ↗

ZEB2, a master regulator of the epithelial–mesenchymal transition, mediates trophoblast differentiationSemantic proximity Read ↗

MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cellsSemantic proximity Read ↗

The Attenuation of Trophoblast Invasion Caused by the Downregulation of EZH2 Is Involved in the Pathogenesis of Human Recurrent MiscarriageSemantic proximity Read ↗

The decreased lncRNA ZEB2‐AS1 in pre‐eclampsia controls the trophoblastic cell line HTR‐8/SVneo's invasive and migratory abilities via the miR‐149/PGF axisSemantic proximity Read ↗

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