Article
Polymorphism of OAS2 rs739901 C/A Involves the Susceptibility to EV71 Infection in Chinese Children.
Current medical science - 1 Aug 2018
Tan Yu-Xia, Wang Hui, Lv Hua, Liu Pei-Pei, Xia Shun-Gang, Wang Yu, Wang Gao-Yan, Guo Ya, Liu Ye-Dan, Yang Cheng-Qing, Chen Li-Ping, Chen Zong-Bo
Abstract excerpt
This study aimed to assess the relationship of OAS2 rs739901 5,-flanking C/A polymorphisms with the susceptibility to Enterovirus-71 (EV71) infection. We investigated 294 hand-foot-mouth disease (HFMD) Chinese children with EV71 infection (165 mild cases and 129 encephalitis cases). The improved multiplex ligation detection reaction (iMLDR) technique was used to test the genotypes. In EV71-infected patients, the...
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