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Article

Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome.

Cardiovascular therapeutics - 1 Jan 2019

Peng Wenxing, Shi Xiujin, Xu Xiaoyu, Lin Yang

Abstract excerpt

OBJECTIVE: The objective of this study is to explore the relationships of the effects of CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high platelet responsiveness (HPR) by thrombelastography in patients with acute coronary syndrome (ACS). METHODS: 459 ACS patients with aspirin and clopidogrel were enrolled in this observational case control study from July 13, 2015, to...

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Identifiers

PMID: 31772608
DOI: 10.1155/2019/3470145
PMCID: PMC6739775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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