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[Two Cases of Colorectal Cancer with SRC Amplification].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Nov 2017

Oyanagi Hidehito, Shimada Yoshifumi, Yagi Ryoma, Tajima Yosuke, Ichikawa Hiroshi, Nakano Mae, Nakano Masato, Nagahashi Masayuki, Sakata Jun, Kameyama Hitoshi, Kobayashi Takashi, Nogami Hitoshi, Maruyama Satoshi, Takii Yasumasa, Wakai Toshifumi

Abstract excerpt

Carcinoma with elevated SRC expression is associated with distant metastasis and drug resistance. We report 2 cases of SRC amplification observed after retrospective comprehensive genomic sequencing. Case 1 was a 62-year-old man who had RAS wild-type stage IV carcinoma of the sigmoid colon with multiple liver metastases in both lobes. He underwent low anterior resection and systemic chemotherapy was initiated to...

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PMID: 29394766

Genes

SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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