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Article

Role of IFT88 in icariin‑regulated maintenance of the chondrocyte phenotype.

Molecular medicine reports - 1 Apr 2018

Xiang Wei, Zhang Jiaming, Wang Rui, Wang Limei, Wang Shengjie, Wu Yingxing, Dong Yonghui, Guo Fengjing, Xu Tao

Abstract excerpt

Maintenance of the chondrocyte phenotype is crucial for cartilage repair during tissue engineering. Intraflagellar transport protein 88 (IFT88) is an essential component of primary cilia, shuttling signals along the axoneme. The hypothesis of the present study was that IFT88 could exert an important role in icariin‑regulated maintenance of the chondrocyte phenotype. To this end, the effects of icariin on...

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Share to Cartilage, Articular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29393439
DOI: 10.3892/mmr.2018.8486
PMCID: PMC5865960

Genes

IFT88
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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