Article
IFT88 influences chondrocyte actin organization and biomechanics.
Osteoarthritis and cartilage - 1 Mar 2016
Wang Z, Wann A K T, Thompson C L, Hassen A, Wang W, Knight M M
Abstract excerpt
OBJECTIVES: Primary cilia are microtubule based organelles which control a variety of signalling pathways important in cartilage development, health and disease. This study examines the role of the intraflagellar transport (IFT) protein, IFT88, in regulating fundamental actin organisation and mechanics in articular chondrocytes. METHODS: The study used an established chondrocyte cell line with and without...
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