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JNK regulates ciliogenesis through the interflagellar transport complex and actin networks

30 Aug 2023

Abstract excerpt

The c-Jun N-terminal kinase (JNK) regulates various important physiological processes. Although the JNK pathway has been under intense investigation for over 20 yr, its complexity is still perplexing, with multiple protein partners underlying the diversity of its activity. We show that JNK is associated with the basal bodies in both primary and motile cilia. Loss of JNK disrupts basal body migration and docking...

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PMID: 37851005
DOI: 10.1083/jcb.202303052

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