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Article

Whole exome sequencing of benign pulmonary metastasizing leiomyoma reveals mutation in the BMP8B gene.

BMC medical genetics - 31 Jan 2018

Sõritsa Deniss, Teder Hindrek, Roosipuu Retlav, Tamm Hannes, Laisk-Podar Triin, Soplepmann Pille, Altraja Alan, Salumets Andres, Peters Maire

Abstract excerpt

BACKGROUND: Benign metastasizing leiomyoma (BML) is an orphan neoplasm commonly characterized by pulmonary metastases consisting of smooth muscle cells. Patients with BML have usually a current or previous uterine leiomyoma, which is therefore suggested to be the most probable source of this tumour. The purpose of this case report was to determine the possible genetic grounds for pulmonary BML. CASE PRESENTATION:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29386003
DOI: 10.1186/s12881-018-0537-5
PMCID: PMC5793349

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