Article
Characterization of a Unique Outer Membrane Protein Required for Oxidative Stress Resistance and Virulence of Francisella tularensis.
Journal of bacteriology - 15 Apr 2018
Alqahtani Maha, Ma Zhuo, Ketkar Harshada, Suresh Ragavan Varadharajan, Malik Meenakshi, Bakshi Chandra Shekhar
Abstract excerpt
Francisella tularensis, the causative agent of tularemia, lacks typical bacterial virulence factors and toxins but still exhibits extreme virulence. The bacterial multidrug efflux systems consist of an inner membrane, a transmembrane membrane fusion protein, and an outer membrane (OM) component that form a contiguous channel for the secretion of a multitude of bacterial products. Francisella contains three...
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