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Pathogenicity determinant protein E is a <i>Francisella</i> type VI secretion system effector protein that modulates host death

2024-11-25

Abstract excerpt

Francisella tularensis is a highly pathogenic Gram-negative intracellular bacterial pathogen and the etiologic agent of tularemia, a fatal zoonotic disease that poses a threat to global public health. F. tularensis virulence is mediated by genes on the Francisella pathogenicity island (FPI), which encodes a unique contractile secretion apparatus with functional and structural similarity to bacterial type VI secr...

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Literature Corpus work
a3c8caa2-b560-5c27-a851-aaab64949838
DOI
10.1101/2024.11.25.624902
Open publication

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Pathogenicity determinant protein E is a <i>Francisella</i> type VI secretion system effector protein that modulates host deathDOI 10.1101/2024.11.25.624902
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