Article
Characterization of rifampin-resistant isolates of Mycobacterium tuberculosis from Sichuan in China.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2013
Tang Ke, Sun Honghu, Zhao Yuding, Guo Jianhua, Zhang Congcong, Feng Qin, He Yongquan, Luo Mei, Li Yuqing, Sun Qun
Abstract excerpt
Rifampin is a key component of standard short-course first-line therapy against Mycobacterium tuberculosis, and rifampin resistance of this pathogen has been reported to be related to rpoB gene mutations. The objective of this study was to characterize the rpoB gene mutations in rifampin-resistant M. tuberculosis isolates circulated in Sichuan. Sequencing of rpoB gene and spoligotyping were performed on 268...
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