Article
Host genetic variation and its microbiome interactions within the Human Microbiome Project.
Genome medicine - 29 Jan 2018
Kolde Raivo, Franzosa Eric A, Rahnavard Gholamali, Hall Andrew Brantley, Vlamakis Hera, Stevens Christine, Daly Mark J, Xavier Ramnik J, Huttenhower Curtis
Abstract excerpt
BACKGROUND: Despite the increasing recognition that microbial communities within the human body are linked to health, we have an incomplete understanding of the environmental and molecular interactions that shape the composition of these communities. Although host genetic factors play a role in these interactions, these factors have remained relatively unexplored given the requirement for large population-based...
Topics
- Genetic Variation
- Genotype
- Humans
- Metagenome
- Microbiota
- Principal Component Analysis
- Sequence Analysis, DNA
- Tissue Donors