Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human and bacterial genetic variation shape oral microbiomes and health.

Nature - 1 Mar 2026

Kamitaki Nolan, Handsaker Robert E, Hujoel Margaux L A, Mukamel Ronen E, Usher Christina L, McCarroll Steven A, Loh Po-Ru

Abstract excerpt

Human genetic variation influences all aspects of our biology, including the oral cavity1-3, through which nutrients and microbes enter the body. Yet it is largely unknown which human genetic variants shape a person's oral microbiome and potentially promote its dysbiosis3-5. We characterized the oral microbiomes of 12,519 people by re-analysing whole-genome sequencing reads from previously sequenced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dysbiosis
Share to Fucosyltransferases
Share to Galactoside 2-alpha-L-fucosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Health

Share to Host Microbial Interactions

Share to Microbiota

Share to Saliva

Source

Open in PubMed Open full text

Identifiers

PMID: 41606319
DOI: 10.1038/s41586-025-10037-7
PMCID: PMC12979206

Genes

FUT2
PITX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human and bacterial genetic variation shape oral microbiomes and health.PMID 41606319Read ↗

Human and bacterial genetic variation shape oral microbiomes and healthSemantic proximity Read ↗

Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiomeSemantic proximity Read ↗

Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiomeSemantic proximity Read ↗

Host genetic control of the oral microbiome and its links to human metabolism and immunitySemantic proximity Read ↗

Genome-wide association study identifies host genetic variants influencing oral microbiota diversity and metabolic health.Semantic proximity Read ↗

Host genetic variation and its microbiome interactions within the Human Microbiome Project.Semantic proximity Read ↗

The Landscape of Genetic Content in the Gut and Oral Human MicrobiomeSemantic proximity Read ↗

Human salivary amylase gene copy number impacts oral and gut microbiomesSemantic proximity Read ↗

Human Salivary Amylase Gene Copy Number Impacts Oral and Gut MicrobiomesSemantic proximity Read ↗

The Oral Microbiome Is a Population-Scale Readout of the Exposome, Age, and Systemic HealthSemantic proximity Read ↗

Host Genetic Control of the Oral Microbiome in Health and Disease.Semantic proximity Read ↗

Population-scale Characterization of the Oral Microbiome and Associations with Metabolic HealthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.