Article
Genomic variation landscape of the human gut microbiome.
Nature - 3 Jan 2013
Schloissnig Siegfried, Arumugam Manimozhiyan, Sunagawa Shinichi, Mitreva Makedonka, Tap Julien, Zhu Ana, Waller Alison, Mende Daniel R, Kultima Jens Roat, Martin John, Kota Karthik, Sunyaev Shamil R, Weinstock George M, Bork Peer
Abstract excerpt
Whereas large-scale efforts have rapidly advanced the understanding and practical impact of human genomic variation, the practical impact of variation is largely unexplored in the human microbiome. We therefore developed a framework for metagenomic variation analysis and applied it to 252 faecal metagenomes of 207 individuals from Europe and North America. Using 7.4 billion reads aligned to 101 reference species,...
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