Article
Human genetic variation and the gut microbiome in disease.
Nature reviews. Genetics - 1 Nov 2017
Hall Andrew Brantley, Tolonen Andrew C, Xavier Ramnik J
Abstract excerpt
Taxonomic and functional changes to the composition of the gut microbiome have been implicated in multiple human diseases. Recent microbiome genome-wide association studies reveal that variants in many human genes involved in immunity and gut architecture are associated with an altered composition of the gut microbiome. Although many factors can affect the microbial organisms residing in the gut, a number of...
Topics
- Dysbiosis
- Gastrointestinal Microbiome
- Genetic Variation
- Humans