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Article

Junctional adhesion molecule C (JAM-C) dimerization aids cancer cell migration and metastasis.

Biochimica et biophysica acta. Molecular cell research - 1 Apr 2018

Garrido-Urbani Sarah, Vonlaufen Alain, Stalin Jimmy, De Grandis Maria, Ropraz Patricia, Jemelin Stéphane, Bardin Florence, Scheib Holger, Aurrand-Lions Michel, Imhof Beat A

Abstract excerpt

Most cancer deaths result from metastasis, which is the dissemination of cells from a primary tumor to distant organs. Metastasis involves changes to molecules that are essential for tumor cell adhesion to the extracellular matrix and to endothelial cells. Junctional Adhesion Molecule C (JAM-C) localizes at intercellular junctions as homodimers or more affine heterodimers with JAM-B. We previously showed that the...

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Identifiers

PMID: 29378216
DOI: 10.1016/j.bbamcr.2018.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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