Article
[Variants in the TNFA, IL6 and IFNG genes are associated with the dengue severity in a sample from Colombian population].
Biomedica : revista del Instituto Nacional de Salud - 1 Dec 2017
Avendaño-Tamayo Efren, Campo Omer, Chacón-Duque Juan Camilo, Ramírez Ruth, Rojas Winston, Agudelo-Flórez Piedad, Bedoya Gabriel, Restrepo Berta Nelly
Abstract excerpt
INTRODUCTION: The genetic makeup of the host contributes to the clinical profile of dengue. This could be due to the effect of variants in the genes encoding pro-inflammatory cytokines. OBJECTIVE: To evaluate the association between the variants of three polymorphisms in TNFA, IL6 and IFNG candidate genes with dengue severity in a sample of Colombian population. MATERIALS AND METHODS: We evaluated the rs1800750,...
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