Article
Association of Genetic Polymorphisms in TLR3, TLR4, TLR7, and TLR8 with the Clinical Forms of Dengue in Patients from Veracruz, Mexico.
Viruses - 29 Oct 2020
Posadas-Mondragón Araceli, Aguilar-Faisal José Leopoldo, Zuñiga Gerardo, Magaña Jonathan Javier, Santiago-Cruz José Angel, Guillén-Salomón Edith, Alcántara-Farfán Verónica, Arellano-Flores María Luisa, Salas-Benito Juan Santiago, Neri-Bazán Rocío M, Luna-Rojas Lucero, Avila-Trejo Amanda Marineth, Chávez-Negrete Adolfo
Abstract excerpt
Dengue manifestations range from a mild form, dengue fever (DF), to more severe forms such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). The ability of the host to present one of these clinical forms could be related to polymorphisms located in genes of the Toll-like receptors (TLRs) which activate the pro-inflammatory response. Therefore, the genotyping of single nucleotide genetic...
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