Article
African genetic ancestry is associated with a protective effect on Dengue severity in colombian populations.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
Chacón-Duque Juan Camilo, Adhikari Kaustubh, Avendaño Efren, Campo Omer, Ramirez Ruth, Rojas Winston, Ruiz-Linares Andrés, Restrepo Berta Nelly, Bedoya Gabriel
Abstract excerpt
The wide variation in severity displayed during Dengue Virus (DENV) infection may be influenced by host susceptibility. In several epidemiological approaches, differences in disease outcomes have been found between some ethnic groups, suggesting that human genetic background has an important role in disease severity. In the Caribbean, It has been reported that populations of African descent present considerable...
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