Pleiotropy of ABO gene: correlation of rs644234 with E-selectin and lipid levels.

doi:10.1515/cclm-2017-0347

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Article

Pleiotropy of ABO gene: correlation of rs644234 with E-selectin and lipid levels.

Clinical chemistry and laboratory medicine - 25 Apr 2018

Arguinano Alex-Ander Aldasoro, Ndiaye Ndeye Coumba, Masson Christine, Visvikis-Siest Sophie

Abstract excerpt

BACKGROUND: The ABO gene has been widely studied and associated with many different diseases such as myocardial infarction and diabetes. Pleiotropic effects of the ABO locus have been demonstrated. Indeed it affects different phenotypes such as E- and P-selectins, triglycerides and total cholesterol. The goal of this work was to study the SNP rs644234 located in the ABO gene with different phenotypes related with...

Topics

ABO Blood-Group System
Adult
E-Selectin
Female
Genotype
Humans
Lipids
Male
Phenotype
Polymorphism, Genetic

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PMID: 29373315
DOI: 10.1515/cclm-2017-0347

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