Article
Identification and replication of novel genetic variants of ABO gene to reduce the incidence of diseases and promote longevity by modulating lipid homeostasis.
Aging - 22 Nov 2021
Ni Xiaolin, Bai Chen, Nie Chao, Qi Liping, Liu Yifang, Yuan Huiping, Zhu Xiaoquan, Sun Liang, Zhou Qi, Li Yan, Zhen Hefu, Su Huabing, Li Rongqiao, Lan Rushu, Pang Guofang, Lv Yuan, Zhang Wei, Yang Fan, Yao Yao, Chen Chen, Wang Zhaoping, Gao Danni, Zhang Nan, Zhang Shenqi, Zhang Li, Wu Zhu, Hu Caiyou, Zeng Yi, Yang Ze
Abstract excerpt
Genes related to human longevity have not been studied so far, and need to be investigated thoroughly. This study aims to explore the relationship among ABO gene variants, lipid levels, and longevity phenotype in individuals (≥90yrs old) without adverse outcomes. A genotype-phenotype study was performed based on 5803 longevity subjects and 7026 younger controls from the Chinese Longitudinal Healthy Longevity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.