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Article

Genetic variation in IL28B (IFNL3) and response to interferon-alpha treatment in myeloproliferative neoplasms.

European journal of haematology - 1 May 2018

Lindgren Marie, Samuelsson Jan, Nilsson Lars, Knutsen Håvar, Ghanima Waleed, Westin Johan, Johansson Peter L, Andréasson Björn

Abstract excerpt

OBJECTIVE: In myeloproliferative neoplasms (MPN), interferon-alpha (IFN-α) is an effective treatment with disease-modifying properties but currently with no clear predictors of treatment outcome. Recent genomewide association studies in chronic hepatitis C have found a strong influence of genetic polymorphism near the IL28B (IFNL3) gene in response to IFN-α treatment. In this study, we sought to evaluate the...

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PMID: 29369421
DOI: 10.1111/ejh.13034

Genes

IFNL3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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