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Article

The role of genetic markers in hepatitis C virus therapy: a major step for individualized care.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2011

McHutchison John G

Abstract excerpt

It has been understood for some time that the treatment outcome of hepatitis C virus (HCV) infection is influenced by host genetic factors. Three independent genome-wide association studies have recently identified that a genetic variation in the IL28B gene [interferon-λ3 (IFN-λ3)] determines the outcome of IFN-α-based therapy in patients with genotype 1 chronic hepatitis C infection. This genetic polymorphism is...

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Identifiers

PMID: 21205135
DOI: 10.1111/j.1478-3231.2010.02389.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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