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Article

The impact of genetic variation in IL28B, IFNL4 and HLA genes on treatment responses against chronic hepatitis C virus infection.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2017

Sakhaee Fatemeh, Ghazanfari Morteza, Vaziri Farzam, Jamnani Fatemeh Rahimi, Davari Mehdi, Gharibzadeh Safoora, Fateh Roohollah, Abdolrahimi Farid, Dizaji Shahin Pourazar, Fateh Abolfazl, Siadat Seyed Davar

Abstract excerpt

Single nucleotide polymorphisms (SNPs) near the interleukin-28B (IL28B), interferon lambda 4 (IFNL4) and the human leukocyte antigen (HLA) gene are associated with treatment responses in patients with chronic hepatitis C (CHC) virus infection treated with pegylated interferon-α and ribavirin (pegIFN-α/RBV). We compared the role of IL28B SNPs (rs12979860, rs12980275, and rs8099917), IFNL4 ss469415590 and HLA...

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Identifiers

PMID: 28739427
DOI: 10.1016/j.meegid.2017.07.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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