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Article

The assembly mechanism of coiled-coil domains of the yeast cargo receptors Emp46p/47p and the mutational alteration of pH-dependency of complex formation.

Journal of biochemistry - 1 May 2018

Kato Koichi, Furuhashi Takahisa, Kato Koichi, Oda Akifumi, Kurimoto Eiji

Abstract excerpt

The coiled-coil domains of the putative yeast cargo receptors Emp46p and Emp47p are responsible for their complex-formation in the Endoplasmic Reticulum. In vitro experiments using coiled-coil domains (Emp46pcc/47pcc) have indicated that formation of the hetero-complex is pH-dependent and that amino acid Glu303 of Emp46pcc is a key residue in this process. In this study, we investigated the effects of various...

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PMID: 29361014
DOI: 10.1093/jb/mvy011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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