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Article

Structure and activation mechanism of the hexameric plasma membrane H+-ATPase.

Nature communications - 8 Nov 2021

Zhao Peng, Zhao Chaoran, Chen Dandan, Yun Caihong, Li Huilin, Bai Lin

Abstract excerpt

The S. cerevisiae plasma membrane H+-ATPase, Pma1, is a P3A-type ATPase and the primary protein component of the membrane compartment of Pma1 (MCP). Like other plasma membrane H+-ATPases, Pma1 assembles and functions as a hexamer, a property unique to this subfamily among the larger family of P-type ATPases. It has been unclear how Pma1 organizes the yeast membrane into MCP microdomains, or why it is that Pma1...

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Identifiers

PMID: 34750373
DOI: 10.1038/s41467-021-26782-y
PMCID: PMC8575881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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