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Article

Association between SCN1A gene polymorphisms and drug resistant epilepsy in pediatric patients.

Seizure - 1 Feb 2018

Margari Lucia, Legrottaglie Anna R, Vincenti Alessandra, Coppola Giangennaro, Operto Francesca F, Buttiglione Maura, Cassano Amalia, Bartolomeo Nicola, Mariggiò Maria A

Abstract excerpt

PURPOSE: "Single Nucleotide Polymorphisms (SNPs)" could be an important explanation of drug resistance in epilepsy. The aim of this study was to investigate if genetic polymorphisms (SNPs) of the SCN1A gene could influence the response to anti - epileptic drugs (AED) and if they could predispose to a drug resistant epilepsy in pediatric patients. METHODS: We investigated SNPs in exon and intronic regions of the...

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Identifiers

PMID: 29353705
DOI: 10.1016/j.seizure.2018.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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