SCN1AIVS5-91G>A polymorphism is associated with susceptibility to epilepsy but not with drug responsiveness.

doi:10.1016/j.biochi.2013.02.006

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Article

SCN1AIVS5-91G>A polymorphism is associated with susceptibility to epilepsy but not with drug responsiveness.

Biochimie - 1 Jun 2013

Kumari Ritu, Lakhan Ram, Kumar Surendra, Garg R K, Misra U K, Kalita J, Mittal Balraj

Abstract excerpt

Sodium channel alpha subunit type 1 (SCN1A) is voltage gated ion channel which plays critical role in membrane excitability. A common SCN1A IVS5-91G>A (rs3812718) allele has been attributed to be a possible modifying factor for epilepsy susceptibility and therapeutic response. In the present study, we enrolled 485 epilepsy patients and 298 age-sex matched controls free of neurological deficits. Therapeutic...

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PMID: 23466530
DOI: 10.1016/j.biochi.2013.02.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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