Article
Clopidogrel response variability: impact of genetic polymorphism and platelet biomarkers for predicting adverse outcomes poststenting.
American journal of therapeutics - 1 Jan 2000
Golukhova Elena Z, Ryabinina Mariya N, Bulaeva Naida I, Grigorian Marina V, Kubova Maida Ch, Serebruany Victor L
Abstract excerpt
The aim of this study was to triage platelet reactivity and adverse vascular outcomes after dual antiplatelet therapy due to percutaneous coronary intervention (PCI) dependent on CYP2C19*2 and CYP2C19*3 genotypes in patients with coronary artery disease. Fifty-five patients with coronary artery disease were studied serially pre-PCI and post-PCI. Platelet reactivity was assessed by conventional light transmission...
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