Article
The DNA helicase RTEL1 is involved in the repair of replicative DNA damage independently of the alternative end joining and the DNA-protein cross-link repair pathways in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 May 2026
Goldkuhle Lara, Lechner Laura, Capdeville Niklas, Dorn Annika, Puchta Holger
Abstract excerpt
Recent studies indicate that the Fe-S DNA helicase RTEL1 plays an important role in replicative DNA repair in plants. Since non-homologous end joining (NHEJ) and DNA-protein cross-link (DPC) repair also protect DNA replication in Arabidopsis, we set out to further define the interactions of RTEL1 and these pathways by analyzing double mutants. Plants with simultaneous defects in the alternative NHEJ factor POLQ...
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