Article
Homologous recombination in planta is stimulated in the absence of Rad50.
EMBO reports - 1 Apr 2001
Gherbi H, Gallego M E, Jalut N, Lucht J M, Hohn B, White C I
Abstract excerpt
Chromosomal double-strand DNA breaks must be repaired; in the absence of repair the resulting acentromeric (and telomereless) fragments may be lost and/or the broken DNA ends may recombine causing general chromosomal instability. The Rad50/Mre11/Xrs2 protein complex acts at DNA ends and is implicated in both homologous and non-homologous recombination. We have isolated a rad50 mutant of the plant Arabidopsis...
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