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Article

Genetic Association Analysis of Drusen Progression.

Investigative ophthalmology & visual science - 1 Apr 2016

Hoffman Joshua D, van Grinsven Mark J J P, Li Chun, Brantley Milam, McGrath Josephine, Agarwal Anita, Scott William K, Schwartz Stephen G, Kovach Jaclyn, Pericak-Vance Margaret, Sanchez Clara I, Haines Jonathan L

Abstract excerpt

PURPOSE: Age-related macular degeneration is a common form of vision loss affecting older adults. The etiology of AMD is multifactorial and is influenced by environmental and genetic risk factors. In this study, we examine how 19 common risk variants contribute to drusen progression, a hallmark of AMD pathogenesis. METHODS: Exome chip data was made available through the International AMD Genomics Consortium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27116550
DOI: 10.1167/iovs.15-18571
PMCID: PMC4849854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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