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Article

MCL-1 is a prognostic indicator and drug target in breast cancer

16 Jan 2018

Abstract excerpt

Analysis of publicly available genomic and gene expression data demonstrates that MCL1 expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl-2 family members, the short half-life of MCL-1 protein led us to investigate MCL-1 protein expression in a breast cancer tissue microarray and correlate this with clinical data. Here, we report associations between high MCL-1 and poor...

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PMID: 29339815
DOI: 10.1038/s41419-017-0035-2

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